Net4Science involved in a multi-target international study against neurodegenerative diseases

The international cooperation in scientific research is a key point of success. Recently on European Journal of Medicinal Chemistry (Elsevier edition) a special issue on multi-target drug discovery (MTDD) was launched. The COST rules allow to support the open access version contribution if three or more different countries are involved in the publication. Among the currently accepted manuscripts one fulfilled all items within the third grant period of the MuTaLig COST Action. The topic is related to the design and development of MTDD compounds able to exert beneficial affect against neurodegenerations, and especially Alzheimer disease. The work is carried out by the collaboration of Portuguese, Spanish and Italian teams, including components of the Net4Science academic spinoff. The manuscript is freely accessible at this link https://doi.org/10.1016/j.ejmech.2019.04.026.

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Net4Science contributes to an international review in the field of drug-food interactions

One of the major unsolved problems in oral therapies is due to the issue of drug-food interactions. The cooperative international COST Action CA16205 UNGAP www.ungap.eu, devoted to focus the attention on this topic, releases a up-to-date review manuscript on the European Journal of Pharmaceutical Sciences, volume 134, pages 31–59. Net4Science gives a contribution in collaboration with more than ten research teams mostly belonging to several European institutions: Greifswald (Germany), Leuven (Belgium), Basel (Switzerland), Utrecht (the Netherlands), Athens (Greece), Prague and Hradec Králové (Czech Republic), Zagreb (Croatia), London and Nottingham (United Kingdom). The review is freely accessible as open access manuscript at www.sciencedirect.com/science/article/pii/S0928098719301411

Net4Science and COST Action MuTaLig dissemination

In the third grant period of the COST Action CA15135 “Multi-target paradigm for innovative ligand identification in the drug discovery process (MuTaLig)” the MC management has indicated Net4Science as provider of some dissemination services related to this European cooperation, including more than 30 different countries. Net4Science is now managing about the website www.mutalig.eu and has just created the YouTube Net4Science channel www.youtube.com/channel/UC9Kb8ulRM0jSKvwVHhdklRw. You can register for free at this channel and from today access to three tutorial videos related to the use of the Chemotheca tool http://chemotheca.unicz.it . This is the first international collaboration of the Net4Science spin-off in the strategic field of the hi-quality scientific dissemination.

Tutorial Chemotheca – Part 1: Introduction and Registration

Tutorial Chemotheca – Part 2: Advanced Search Database

Tutorial Chemotheca – Part 3: Uploading-Editing Molecules

Net4Science on Frontiers in Chemistry

Net4Science has published its first scientific article at the conclusion of the research topic on the international journal Frontiers in Chemistry (IF 4.155) dedicated to the multi-target drug discovery. The Editorial entitled “Multi-target-directed ligands (MTDL) as challenging research tools in drug discovery: from design to pharmacological evaluation” is available as open access document on line at www.frontiersin.org/research-topics/7369/multi-target-directed-ligands-mtdl-as-challenging-research-tools-in-drug-discovery-from-design-to-ph with all manuscripts accepted by the peer-reviewing process within the research topic. It has been also referenced on Medline at the link www.ncbi.nlm.nih.gov/pubmed/30834243 and can be directly downloaded from https://doi.org/10.3389/fchem.2019.00071.

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