January

1. Salpini R.; Alkhatib M.; Costa G.; Piermatteo L.; Ambrosio F.A.; Di Maio V.C.; Scutari R.; Duca L.; Berno G.; Fabeni L.; Alcaro S.; Ceccherini-Silberstein F.; Artese A.; Svicher V.; Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control. J Antimicrob Chemother 2021, Jan 19;76(2):396-412.
2. Romeo I.; Mesiti F.; Lupia A.; Alcaro S.; Current Updates on Naturally Occurring Compounds Recognizing SARS-CoV-2 Druggable Targets. Molecules 2021, Jan 26;26(3):632.

February

3. Ortuso, F.; Mercatelli D.; Guzzi P.H.; Giorgi F.M.; Structural genetics of circulating variants affecting the SARS-CoV-2 spike/human ACE2 complex. J Biomol Struct Dyn 2021, Feb 13:1-11.
DOI: 10.1080/07391102.2021.1886175

4. Spanò, V.; Barreca, M.; Rocca, R.; Bortolozzi, R.; Bai, R.; Carbone, A.; Raimondi, M.L.; Palumbo Piccionello A.; Montalbano, A.; Alcaro, S.;
Hamel, E.; Viola, G.; Barraja, P.; (2020). Insight on [1, 3] thiazolo [4, 5-e] isoindoles as tubulin polymerization inhibitors. Eur J Med Chem 2021, Feb 15;212:113122.
DOI: 10.1016/j.ejmech.2020.113122


5. Vasconcelos, M.H.; Alcaro, S.; Arechavala-Gomeza, V.; Baumbach, J.; Borges, F.; Brevini, T.A.L., Rivas, J.L.; Devaux,Y.; Hozak, P.; Keinänen-Toivola, M.M.; Lattanzi, G.; Mohr, T.; Murovska, M.; Prusty, B.K.; Quinlan, R.A.; Pérez-Sala, D.; Scheibenbogen, C.; Schmidt, H.H.H.W.; Silveira, I.; Tieri, P.; Tolios, A.; Riganti, C.; Joining European Scientific Forces to Face Pandemics. Trends Microbiol 2021, Feb;29(2):92-97.
DOI: 10.1016/j.tim.2020.10.008

6. Costa G.; Artese A.; Ortuso F.; Alcaro S.; From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds. Methods Mol Biol 2021;2266:263-277.
DOI: 10.1007/978-1-0716-1209-5_15

March

7. Mesiti F.; Maruca A.; Silva V.; Rocca R.; Fernandes C.; Remião F.; Uriarte E.; Alcaro S.; Gaspar A.; Borges F.; 4-Oxoquinolines and monoamine oxidase: When tautomerism matters. Eur J Med Chem 2021, Mar 5;213:113183.
DOI: 10.1016/j.ejmech.2021.113183

 

April

8. Deplano A.; Karlsson J.; Moraca F.; Svensson M.; Cristiano C.; Morgillo C.M.; Fowler C.J.; Russo R.; Catalanotti B.; Onnis V.; Design, synthesis and in vitro and in vivo biological evaluation of flurbiprofen amides as new fatty acid amide hydrolase/cyclooxygenase-2 dual inhibitory potential analgesic agents. J Enzyme Inhib Med Chem 2021 Apr 36:1, 940-953
DOI: 10.1080/14756366.2021.1875459

 

May

9. Senatore E.; Chiuso F.; Rinaldi L.; Intartaglia D.; Delle Donne R.; Pedone E.; Catalanotti B.; Pirone L.; Fiorillo B.; Moraca F.; Giamundo G.; Scala G.; Raffeiner A.; Torres-Quesada O.; Stefan E.; Kwiatkowski M.; van Pijkeren A.; Morleo M.; Franco B.; Garbi C.; Conte I.; Feliciello A.; The TBC1D31/praja2 complex controls primary ciliogenesis through PKA-directed OFD1 ubiquitylation. EMBO J 2021 May 17;40(10):e106503.

10. Ambrosio F.A.; Coricello A.; Costa G.; Lupia A.; Micaelli M.; Marchesi N.; Sala F.; Pascale A.; Rossi D.; Vasile F.; Alcaro S.; Collina S.; Identification of Compounds Targeting HuD. Another Brick in the Wall of Neurodegenerative Disease Treatment. J Med Chem 2021 Jul 22;64(14):9989-10000.
DOI: 10.1021/acs.jmedchem.1c00191

August

11. Mesiti F.; Gaspar A.; Chavarria D.; Maruca A.; Rocca R.; Gil Martins E.; Barreiro S.; Silva R.; Fernandes C.; Gul S, Keminer O.; Alcaro S.; Borges F.; Mapping Chromone-3-Phenylcarboxamide Pharmacophore: Quid Est Veritas? J Med Chem 2021 Aug 12;64(15):11169-11182. DOI: 10.1021/acs.jmedchem.1c00191

 

12. Murdocca, M.; Citro, G.; Romeo, I.; Lupia, A.; Miersch, S.; Amadio, B.; Bonomo, A.; Rossi, A.; Sidhu, S.S.; Pandolfi, P.P.; Alcaro, S.; Sangiuolo, F.C.; Novelli, G. Peptide Platform as a Powerful Tool in the Fight against COVID-19. Viruses 2021, 13, 1667. DOI: 10.3390/v13081667